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Author Topic: Cognition problems found in long-term medical marijuana users  (Read 6451 times)
voodoolily
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Finnuh, munnuh, muhfuh, I enjoy creating new written vernacular, s'all.


WWW
on: March 29, 2011, 03:44:01 PM


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The Legend of Zephyr - a different blog.
Morat20
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Reply #1 on: March 29, 2011, 05:14:05 PM

25 people on one side -- decades of people trying to prove that and failing on the other.....

I'm going with "skepticism". Weed has been so heavily demonized, and so many fucking studies have been done trying to find side-effects, long-term effects, carcinogenic properties --- and every study I've seen in two decades that has found one has had a handful of people, trumpeted loudly in the media, and subsequently dropped out of sight as larger studies failed to find the same thing.

I'm going to predict this goes into the conventional wisdom, doesn't get replicated, and in about two years we'll see another with a totally different claim. I'm starting to think pot's got more long-term studies than aspirin at this point.
MahrinSkel
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Reply #2 on: March 29, 2011, 05:36:59 PM

Considering that cognitive degradation is an inherent part of MS progression, such a small sample means precisely nothing.

--Dave

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Sheepherder
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Reply #3 on: March 29, 2011, 07:26:06 PM

Report is here.

I didn't dig into the full report yet, but the summary doesn't mention detoxing.  We have once again discovered that high people are high.
Morat20
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Reply #4 on: March 29, 2011, 07:30:33 PM

Report is here.

I didn't dig into the full report yet, but the summary doesn't mention detoxing.  We have once again discovered that high people are high.
Supposedly they didn't test anyone who'd smoked in the last 12 hours. According to the critics cited in the last few paragraphs, they didn't do much to account for other meds the MS patients were on.

*shrug*. Don't smoke the stuff myself, but even if that was true -- alcohol fucks your brain long-term too, and that's perfectly legal. :) The whole weed thing just annoys the fuck out of me, simply because it's so obviously an outlier that it offends my sense of fairness.
Sheepherder
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Reply #5 on: March 29, 2011, 09:17:46 PM

Cannabis doesn't detox like most other drugs.  It's fat soluble and water insoluble, ergo it accumulates in your fat tissue and only gets removed via defecation over a period of months.
NiX
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Reply #6 on: March 29, 2011, 09:23:24 PM

Cannabis doesn't detox like most other drugs.  It's fat soluble and water insoluble, ergo it accumulates in your fat tissue and only gets removed via defecation over a period of months.

That sounds rad.
Hawkbit
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Reply #7 on: March 29, 2011, 09:34:35 PM

Where's Bill Hicks when we need him? 

My big issue with this report (and I've only skimmed) was presented in the previous two posts.  If a user detoxes over a period of months, does cognition improve when the drug has left the system?  In skimming, they didn't seem to address that. 

Sheepherder
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Reply #8 on: March 29, 2011, 10:56:01 PM

Data on long term effects is sketchy.  Addicts and dying people aren't good test subjects, and the issue has been thoroughly shitted up by decades of bad science.
Cyrrex
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Reply #9 on: March 30, 2011, 05:48:26 AM

I wonder if it's possible that there may even be other medicinal drugs out there that impair thinking?  Unpossible!

In other news, who gives a shit.

"...maybe if you cleaned the piss out of the sunny d bottles under your desks and returned em, you could upgrade you vid cards, fucken lusers.." - Grunk
voodoolily
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Finnuh, munnuh, muhfuh, I enjoy creating new written vernacular, s'all.


WWW
Reply #10 on: March 30, 2011, 10:07:59 AM

We have once again discovered that high people are high.

This was the gist of what I was saying. Thanks, Science.

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Yegolev
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WWW
Reply #11 on: March 30, 2011, 10:25:56 AM

Where's Bill Hicks when we need him?


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K9
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Reply #12 on: March 30, 2011, 10:26:50 AM

Actual paper in question

From skimming through it I can't spot any obvious methodological flaws. It seems like a fairly typical, well designed cohort study. The conclusion isn't all that surprising, long term there's very little that doesn't alter your body in one way or the other.

Cannabis doesn't detox like most other drugs.  It's fat soluble and water insoluble, ergo it accumulates in your fat tissue and only gets removed via defecation over a period of months.

That sounds rad.

It sounds like utter bollocks.

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Sky
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Reply #13 on: March 30, 2011, 11:12:56 AM

But he said ergo.
Minvaren
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Reply #14 on: March 30, 2011, 11:19:16 AM

Cannabis doesn't detox like most other drugs.  It's fat soluble and water insoluble, ergo it accumulates in your fat tissue and only gets removed via defecation over a period of months.

As far as the stuff "getting out of your system," my understanding is that it's the THC metabolites (not the THC itself, CBD, CBN, or anything else) that work their way out of your fat over the days/weeks (depends on how long/much you used) after you quit.  The readjustment period is your endocannaboid and dopamine systems readjusting to a lack of extra outside stimulation.

That's the main issue I have with the whizz test for pot usage - you're not testing if it's in the bloodstream or if someone's currently using, you're testing past usage.  Everything else on a whizz test only goes back about 48 hours.

"There are many things of which a wise man might wish to remain ignorant." - Ralph Waldo Emerson
Sand
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Reply #15 on: March 30, 2011, 11:34:35 AM

Psssh.
Who needs a scientific study when we have-

Mrbloodworth
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Reply #16 on: March 30, 2011, 11:53:18 AM

Alcohol has zero side effects.

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Paelos
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Error 404: Title not found.


Reply #17 on: March 30, 2011, 12:23:05 PM

Alcohol has zero side effects.

Neither does being a griefer.

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NiX
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Reply #18 on: March 30, 2011, 12:39:39 PM

Shitty threads cause depression and internet rage. Ergo.
Furiously
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WWW
Reply #19 on: March 30, 2011, 12:45:58 PM

Cogito ergo sum...

Sheepherder
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Reply #20 on: March 30, 2011, 10:19:20 PM

It sounds like utter bollocks.

The elimination half-life of THC is approximately 30 hours, you do the math.
Furiously
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WWW
Reply #21 on: March 31, 2011, 02:18:10 AM

Unless you have warlock genes and tigerblood.

I didn't read the study, did it identify how people were cognitively affected? I mean if some short term memory issues are the only problem, still sounds safer than alchols long term effects. Or does it just cognitively make people want snacks?

Sheepherder
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Reply #22 on: March 31, 2011, 03:32:13 PM

Quote
"...difficulties in processing information and short-term verbal memory, and greater lifetime psychopathology"

Again, entirely foreseeable.
Samprimary
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Reply #23 on: April 01, 2011, 05:55:51 AM

"difficulties in processing information and short-term verbal memory, and greater lifetime psychopathology" sounds like something I would expect, and could anecdotally swear to as I watch a whole bunch of my friends smoke themselves into oblivion. But that's all that is. Expectations and anecdote. The scientific findings of what pot actually does to you long term are .. going to take a while to become clear.
apocrypha
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Reply #24 on: April 01, 2011, 11:18:07 PM

Whereas the psychological, physiological and social harms done by, for instance, over-prescribed anti-depressants, alcohol and tobacco are crystal clear and irrefutable.

"Bourgeois society stands at the crossroads, either transition to socialism or regression into barbarism" - Rosa Luxemburg, 1915.
Sheepherder
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Reply #25 on: April 02, 2011, 02:23:42 PM

I would have went with Oxycodone.
Typhon
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Reply #26 on: April 04, 2011, 10:09:51 AM

The study is very straight-forward and if all the pot hadn't thoroughly numbed your skulls it would easly be within your cognitive abilities to grasp it's importance.



 cry
I'm just disappointed with myself that I didn't get to this thread in time for that sentence to be as funny as it deserved.
Lantyssa
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Reply #27 on: April 04, 2011, 03:59:51 PM

It's okay.  We know you would have responded in a more timely manner if your cognitive abilities hadn't been impaired.

Hahahaha!  I'm really good at this!
Mrbloodworth
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Reply #28 on: April 08, 2011, 07:52:58 AM


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