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f13.net  |  f13.net General Forums  |  General Discussion  |  Serious Business  |  Topic: Japan to open Jurassic Park for reals. 0 Members and 1 Guest are viewing this topic.
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Author Topic: Japan to open Jurassic Park for reals.  (Read 4561 times)
WindupAtheist
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on: January 20, 2011, 03:29:20 AM

Okay not really, but the quest to un-extinct a species via cloning is officially underway. I for one really hope this shit works.

Researchers aim to resurrect mammoth in five years.

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K9
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Reply #1 on: January 20, 2011, 06:09:23 AM

I hope they manage to pull this off, and I am sure the methods they will have to develop in order to even attempt this will prove useful in many other applications.

I will register my suspicion that they will fail though, for a host of possible reasons. I mainly wonder about the integrity and quality of the DNA, it is unlikely to be in tip-top quality after so many years.

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Cyrrex
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Reply #2 on: January 20, 2011, 06:36:44 AM

It would be beyond awesome if they succeeded.

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Yegolev
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Reply #3 on: January 20, 2011, 06:59:42 AM

What the article fails to mention is that the resulting mammoth will have very large eyes and shout everything.

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Reply #4 on: January 20, 2011, 07:30:47 AM

I'm with Yeg on this one. It's Japan. It will end up getting repeatedly raped by japanese businessmen. Poor mammoth.
Xuri
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Reply #5 on: January 20, 2011, 07:56:38 AM

I'm with Yeg on this one. It's Japan. It will end up getting repeatedly tentacle-raped by japanese businessmen. Poor mammoth.
Fixed that for you.

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Chimpy
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Reply #6 on: January 20, 2011, 08:01:35 AM

I hope they manage to pull this off, and I am sure the methods they will have to develop in order to even attempt this will prove useful in many other applications.

I will register my suspicion that they will fail though, for a host of possible reasons. I mainly wonder about the integrity and quality of the DNA, it is unlikely to be in tip-top quality after so many years.

Aren't they using the DNA from that Mammoth they excavated almost 100% intact from the Siberian permafrost a few years ago? If I recall, the tissues were all in pretty much "just after dead" state on that thing when they pulled it out.

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MuffinMan
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Reply #7 on: January 20, 2011, 08:41:36 AM

I mainly wonder about the integrity and quality of the DNA, it is unlikely to be in tip-top quality after so many years.

That's where you splice in the frog DNA.

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K9
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Reply #8 on: January 20, 2011, 08:52:57 AM

I hope they manage to pull this off, and I am sure the methods they will have to develop in order to even attempt this will prove useful in many other applications.

I will register my suspicion that they will fail though, for a host of possible reasons. I mainly wonder about the integrity and quality of the DNA, it is unlikely to be in tip-top quality after so many years.

Aren't they using the DNA from that Mammoth they excavated almost 100% intact from the Siberian permafrost a few years ago? If I recall, the tissues were all in pretty much "just after dead" state on that thing when they pulled it out.

I think so, but 34,000 years is still a substantial timeframe, and while bacterial DNA has been resurrected after significantly longer periods (in the order of millions of years old, from ice cores), eukaryotic DNA has less tolerance for errors. It is hard to believe that such long periods where the DNA will have undergone physical and chemical stress will have left it unscarred. Cloning from living tissues is still a somewhat hit-and-miss endeavour, let alone using DNA which has had thousands of years to degrade. That said, I expect they will have to develop methods to patch, repair and splice the DNA which will have widespread uses in synthetic biology, so this is far from a useless endeavour.

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HaemishM
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Reply #9 on: January 20, 2011, 09:25:23 AM

This will end well. I for one welcome our new ancient pachyderm overlords.

Sky
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Reply #10 on: January 20, 2011, 11:44:57 AM

That's where you splice in the frog octopus DNA.
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Reply #11 on: January 20, 2011, 01:13:56 PM

Now I understand why these people are constantly getting attacked by large monsters. You didn't think Godzilla just came outta the ocean now did you?

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Velorath
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Reply #12 on: January 20, 2011, 03:31:06 PM

Now I understand why these people are constantly getting attacked by large monsters. You didn't think Godzilla just came outta the ocean now did you?

So you're saying they might accidentally create Mammothra?
Sir T
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Reply #13 on: January 21, 2011, 01:01:07 PM

Its not so much degradation, its the fact that cells have this annoying habit of  bursting when you freeze them, because the water in them expands. So when you defrost them you have a nice unusuable lump of proteins.

That and the technique they used on Dolly the sheep (electric shock to stimulate the egg to start dividing) actually damages the DNA anyway. That's why Dolly came after 1000s of failures. And she aged too fast.

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Sheepherder
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Reply #14 on: January 21, 2011, 09:59:43 PM

Cell structure and DNA are two very different things.
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Reply #15 on: January 23, 2011, 03:01:43 AM

Holy shit. Jesus really can come back!

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Reply #16 on: January 23, 2011, 09:12:49 AM

Wouldn't it be funny if we extracted DNA from the shroud of Turin and it turns out to be one of the two thieves? Some schmuck with a moniker like Jedediah the Unclean. or something.

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pxib
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Reply #17 on: January 23, 2011, 10:43:27 AM

Blah blah epigenome blah maternal effect blah share a bloodstream blah blah.

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Merusk
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Reply #18 on: January 23, 2011, 11:10:09 AM

Wouldn't it be funny if we extracted DNA from the shroud of Turin and it turns out to be one of the two thieves? Some schmuck with a moniker like Jedediah the Unclean. or something.

At this point it'd be funny if it were actually 2k years old instead of ~800 awesome, for real

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